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Synthetic Vaccines (Synthvaccine): Principles, Design Strategies, and Clinical Applications

1. Core Definition and Fundamental Principles Synthetic vaccines are a class of vaccines engineered de novo using synthetic biology, computational design, and chemical synthesis. Unlike traditional vaccines (live-attenuated or inactivated pathogens), they comprise synthetic components such as: Pepti … Synthetic Vaccines (Synthvaccine): Principles, Design Strategies, and Clinical ApplicationsRead more

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Vector Vaccines: Notable Examples and Applications in Human and Animal Health

Vector Vaccines: Notable Examples and Applications in Human and Animal Health I. Viral Vector Vaccines 1. Human Medicine a. Adenoviral Vectors COVID-19 Vaccines: ChAdOx1 (AstraZeneca): A chimpanzee adenovirus vector delivers the SARS-CoV-2 spike protein gene, achieving ~70% efficacy with a single do … Vector Vaccines: Notable Examples and Applications in Human and Animal HealthRead more

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Splice Genes in Protein Diversity and Tissue-Specific Regulation: Advances and Applications

Splice Genes in Protein Diversity and Tissue-Specific Regulation: Advances and Applications I. Biological Basis of Alternative Splicing and Protein Diversity 1. Prevalence and Molecular Mechanisms Alternative splicing, a central post-transcriptional regulatory mechanism, generates multiple mRNA isof … Splice Genes in Protein Diversity and Tissue-Specific Regulation: Advances and ApplicationsRead more

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Strategies and Recent Advances in Viral Gene-Based Disease Prevention

Strategies and Recent Advances in Viral Gene-Based Disease Prevention The unique biological properties of viral genes—such as high infectivity, target specificity, and programmability—have revolutionized disease prevention. By engineering viral vectors or leveraging viral genome characteristics, sci … Strategies and Recent Advances in Viral Gene-Based Disease PreventionRead more

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Vector Vaccines: A Cornerstone Tool Against Emerging Infections, Cancer, and Genetic Diseases

Vector Vaccines: A Cornerstone Tool Against Emerging Infections, Cancer, and Genetic Diseases Core Mechanisms and Technical Principles Vector vaccines use engineered viruses or bacteria as delivery vehicles to introduce foreign antigen genes into host cells, triggering specific immune responses. Key … Vector Vaccines: A Cornerstone Tool Against Emerging Infections, Cancer, and Genetic DiseasesRead more

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ViralVectorAI: The Role and Future of AI-Driven Viral Vector Technology in Gene Editing

ViralVectorAI: The Role and Future of AI-Driven Viral Vector Technology in Gene Editing The integration of AI and viral vector technology is revolutionizing gene editing, driving advancements in precision, intelligence, and industrial scalability. By optimizing vector design, predicting editing outc … ViralVectorAI: The Role and Future of AI-Driven Viral Vector Technology in Gene EditingRead more