Emerging Applications of Metagenomics and High-Throughput Sequencing The integration of metagenomics and high-throughput sequencing (NGS) is revolutionizing life sciences, medicine, and environmental research by enabling culture-free analysis of microbial communities. This synergy deciphers the comp … Emerging Applications of Metagenomics and High-Throughput SequencingRead more
CRISPR
Recent Advances and Applications of Metagenomics in Microbiome Research
Recent Advances and Applications of Metagenomics in Microbiome Research Metagenomics, a cornerstone methodology in microbiome research, bypasses traditional culturing techniques by directly analyzing the complete genetic material from environmental or host samples. This approach has unveiled the div … Recent Advances and Applications of Metagenomics in Microbiome ResearchRead more
Latest Advances and Future Prospects in Gene Editing, Synthetic Biology, and AI Integration
Latest Advances and Future Prospects in Gene Editing, Synthetic Biology, and AI Integration (2025 Update) I. Gene Editing: From Precision Targeting to Full Gene Integration 1. Breakthrough in evoCAST Gene Editing Tool Achievement: The evoCAST tool, co-developed by David Liu’s team (MIT/Harvard Broad … Latest Advances and Future Prospects in Gene Editing, Synthetic Biology, and AI IntegrationRead more
Advances in Exon Editing for Hemophilia, Spinal Muscular Atrophy, and Cancer Therapy
Advances in Exon Editing for Hemophilia, Spinal Muscular Atrophy, and Cancer Therapy (As of May 2025) I. Spinal Muscular Atrophy (SMA): Restoring SMN Protein Expression 1. Precision Repair of SMN2 Exon 7 Base Editing: A-to-G editing at the SMN2 exon 7 C6T mutation increases splicing efficiency to 99 … Advances in Exon Editing for Hemophilia, Spinal Muscular Atrophy, and Cancer TherapyRead more
Latest Advances in Lipid Nanoparticles (LNPs) for Gene Editing and Cancer Immunotherapy
Latest Advances in Lipid Nanoparticles (lnpdelivery) for Gene Editing and Cancer Immunotherapy (As of May 2025) I. LNP-Driven CRISPR-Cas9 Delivery in Gene Editing 1. Targeting PLK1 in Glioblastoma Technology: Amino-ionizable lipid LNPs encapsulate Cas9 mRNA and sgRNA (targeting PLK1), achieving 70% … Latest Advances in Lipid Nanoparticles (LNPs) for Gene Editing and Cancer ImmunotherapyRead more
Advances in Limb Rehabilitation and Health: Multimodal Integration and Personalized Medical Revolution
Advances in Limb Rehabilitation and Health: Multimodal Integration and Personalized Medical Revolution (As of May 2025) I. Breakthroughs in Intelligent Rehabilitation Robotics 1. Human-Machine Adaptive Systems Lower Limb Rehabilitation Robot (Chinese Academy of Sciences): Uses cantilever force senso … Advances in Limb Rehabilitation and Health: Multimodal Integration and Personalized Medical RevolutionRead more
Contraindications of COVID-19 Antiviral Therapies: A Comprehensive Analysis
Contraindications of COVID-19 Antiviral Therapies: A Comprehensive Analysis (As of May 2025) I. Key Contraindications of Major Antivirals 1. Paxlovid (Nirmatrelvir/Ritonavir) Absolute Contraindications: Hypersensitivity to nirmatrelvir or ritonavir (e.g., Stevens-Johnson syndrome, toxic epidermal ne … Contraindications of COVID-19 Antiviral Therapies: A Comprehensive AnalysisRead more
Comprehensive Analysis of SARS-CoV-2 Variants and Emerging Treatments
Comprehensive Analysis of SARS-CoV-2 Variants and Emerging Treatments (As of May 2025) I. Key Variants and Epidemiological Features 1. Dominant Circulating Variants XBB.1.5 (“Kraken”): Transmissibility: WHO designates it as the most transmissible Omicron subvariant, with a 3–5x higher R0 … Comprehensive Analysis of SARS-CoV-2 Variants and Emerging TreatmentsRead more