The Pivotal Role of High-Precision Sensors in Synthetic Biology High-precision sensors are central to achieving dynamic control, real-time monitoring, and precision design in synthetic biology, with applications spanning fundamental research to industrial deployment. Below, we dissect their multidim … The Pivotal Role of High-Precision Sensors in Synthetic BiologyRead more
CRISPR
Core Challenges in Synthetic Biology Kinetics: A Deep Dive
Core Challenges in Synthetic Biology Kinetics: A Deep Dive I. Foundational Challenges in Model Construction Parameterization Challenges & Data Noise Kinetic models (e.g., ODEs, FBA) for synthetic biosystems rely heavily on experimental parameters such as enzymatic reaction rates (kcatkcat) and … Core Challenges in Synthetic Biology Kinetics: A Deep DiveRead more
Synthetic Biology Kinetics（synbiok）: Theoretical Foundations for Rational Design of Biosystems
Synthetic Biology Kinetics: Theoretical Foundations for Rational Design of Biosystems Synthetic biology kinetics bridges quantitative modeling and biological system engineering, providing a mathematical framework to predict and control the dynamic behavior of engineered biological systems. This disc … Synthetic Biology Kinetics（synbiok）: Theoretical Foundations for Rational Design of BiosystemsRead more
Synthetic Biology: Key Directions in Gene Manipulation
Synthetic Biology: Key Directions in Gene Manipulation I. Foundational Gene-Editing Technologies DNA Synthesis & Assembly Chemical Synthesis: Solid-phase phosphodiester bond-based synthesis produces single-stranded DNA up to 200–300 bp, enabling full gene synthesis (e.g., artificial yeast chromo … Synthetic Biology: Key Directions in Gene ManipulationRead more
Synaptophysin: Biological Expression and Cutting-Edge Advances
Synaptophysin: Biological Expression and Cutting-Edge Advances I. Core Concepts of Synaptophysin Biosynthesis Definition Synaptophysin (SYP), a 38 kDa transmembrane glycoprotein belonging to the tetraspanin family, is predominantly localized on presynaptic vesicle membranes in neurons (constituting … Synaptophysin: Biological Expression and Cutting-Edge AdvancesRead more
Comprehensive Applications of Polymerase Chain Reaction (PCR) Across Diverse Fields
Comprehensive Applications of Polymerase Chain Reaction (PCR) Across Diverse Fields I. Gene Cloning: Precision Amplification and Vector Construction Principles and Procedures PCR enables specific amplification of target DNA fragments through primer design, providing high-purity templates for gene cl … Comprehensive Applications of Polymerase Chain Reaction (PCR) Across Diverse FieldsRead more
In Vivo vs. Ex Vivo Gene Editing Therapies: Key Differences and Future Prospects
In Vivo vs. Ex Vivo Gene Editing Therapies: Key Differences and Future Prospects (as of May 2025) Core Definitions and Technical Pathways Aspect Ex Vivo Gene Editing In Vivo Gene Editing Workflow Cells extracted, edited in vitro, and reinfused Editing tools delivered directly to target tissues/cells … In Vivo vs. Ex Vivo Gene Editing Therapies: Key Differences and Future ProspectsRead more
Gene Editing in Cancer Therapy and Antiviral Research: Recent Advances and Applications
Gene Editing in Cancer Therapy and Antiviral Research: Recent Advances and Applications (as of May 2025) I. Cancer Therapy: Revolutionizing Treatment Paradigms Gene editing technologies (e.g., CRISPR-Cas9, Prime Editing, Base Editing) are reshaping cancer treatment by targeting oncogenes, modulating … Gene Editing in Cancer Therapy and Antiviral Research: Recent Advances and ApplicationsRead more