RNAmod

  Introduction Modified RNA (modRNA), engineered through chemical or enzymatic alterations to nucleosides and backbone structures, has emerged as a transformative tool in vaccine development. By addressing the inherent instability and immunogenicity of natural RNA, modRNA technologies enable th … Harnessing Modified RNA in Vaccine Development: Innovations, Mechanisms, and Clinical ImpactRead more

Introduction Modified RNA (modRNA)—engineered through chemical or enzymatic alterations to nucleosides or backbone structures—has revolutionized biomedical applications by overcoming a critical limitation of natural RNA: its propensity to trigger innate immune responses. By mimicking endogenous RNA … Mechanisms of Immune Evasion by Modified RNA: Molecular Stealth in TherapeuticsRead more

  Introduction Modified RNA (modRNA)—ribonucleic acid molecules chemically or enzymatically altered to enhance stability, functionality, and therapeutic efficacy—has emerged as a cornerstone of precision medicine. By circumventing the limitations of unmodified RNA, such as rapid degradation and … Modified RNA in Modern Medicine: Revolutionizing Therapeutics Through Molecular EngineeringRead more