Lipid Nanoparticles (LNPs) in Gene Therapy and Cancer Treatment: Practical Applications Lipid nanoparticles (LNPs), as non-viral delivery vehicles, have become a core technology in gene therapy and cancer treatment due to their high nucleic acid delivery efficiency, low immunogenicity, and engineeri … Lipid Nanoparticles (LNPs) in Gene Therapy and Cancer Treatment: Practical ApplicationsRead more
tools
RNAScan-RNA Bioinformatics Tools: A Comprehensive Overview
RNAScan-RNA Bioinformatics Tools: A Comprehensive Overview RNA scanning tools are pivotal for decoding RNA functions, structures, and interactions across basic sequence analysis to complex functional predictions. This systematic review categorizes tools by functionality, technical principles, repres … RNAScan-RNA Bioinformatics Tools: A Comprehensive OverviewRead more
Watson-Crick Base Pairing in RNA Sequence-Specific Tools
Watson-Crick Base Pairing in RNA Sequence-Specific Tools Watson-Crick base pairing (A-U/T and G-C) underpins RNA secondary structure stability and sequence specificity. This analysis explores how RNA tools leverage Watson-Crick interactions to achieve sequence-specific recognition and functional reg … Watson-Crick Base Pairing in RNA Sequence-Specific ToolsRead more
GenomEdit and Genetic Disease Therapy: A Comprehensive Analysis of Technological Breakthroughs and Clinical Translation
GenomEdit and Genetic Disease Therapy: A Comprehensive Analysis of Technological Breakthroughs and Clinical Translation 1. Technological Paradigm Shift GenomEdit (Genome Editing) achieves curative treatment for genetic disorders by precisely targeting DNA sequences. Its core technologies include CRI … GenomEdit and Genetic Disease Therapy: A Comprehensive Analysis of Technological Breakthroughs and Clinical TranslationRead more
IntronEdit: A Multidimensional Analysis of Intronic Editing Technology
IntronEdit: A Multidimensional Analysis of Intronic Editing Technology 1. Core Definition and Technical Logic IntronEdit refers to advanced biotechnologies that precisely modify introns—non-coding sequences within genes—to indirectly regulate gene expression, splicing patterns, or epigenetic landsca … IntronEdit: A Multidimensional Analysis of Intronic Editing TechnologyRead more
ExonEdit: Precision Editing of Exons for Therapeutic and Industrial Applications
ExonEdit: Precision Editing of Exons for Therapeutic and Industrial Applications Core Definition Exon: DNA segments within genes that encode proteins, constituting approximately 1.5% of the human genome. ExonEdit (Exon Editing): A biotechnology that precisely modifies exon sequences to regulate prot … ExonEdit: Precision Editing of Exons for Therapeutic and Industrial ApplicationsRead more
Edit omics: Definition, Disciplinary Scope, and Future Applications
编辑组学：定义、学科范围和未来应用 定义和学科范围 Editomics 是“Edit”和“Omics”的合成词，代表了一个科学领域，专注于通过将基因编辑技术与多组学方法（基因组学、转录组学、蛋白质组学等）相结合来系统分析生物编辑事件。其研究范围包括： 基因组编辑组学：使用 CRISPR、碱基编辑等对基因组进行靶向修饰，以研究系统性的生物学影响。 RNA 编辑组学：研究 RNA 水平编辑事件（例如，ADAR 介导的 A-to-I 编辑）及其在疾病中的作用，例如 EDK 数据库中记录的异常 RNA 编辑-疾病关联。 表观遗传编辑组学：调节表观遗传标记（例如，DNA 甲基化、组蛋白修饰）以改变基因表 … Edit omics: Definition, Disciplinary Scope, and Future ApplicationsRead more
GenomEdit: Definition, Technical Principles, and Multidimensional Impact on Humanity
GenomEdit: Definition, Technical Principles, and Multidimensional Impact on Humanity 1. Definition and Core Technologies GenomEdit (genome editing) refers to the precise modification of an organism’s genome using molecular biology techniques, including the insertion, deletion, replacement, or regula … GenomEdit: Definition, Technical Principles, and Multidimensional Impact on HumanityRead more