1. Core Definition and Fundamental Principles Synthetic vaccines are a class of vaccines engineered de novo using synthetic biology, computational design, and chemical synthesis. Unlike traditional vaccines (live-attenuated or inactivated pathogens), they comprise synthetic components such as: Pepti … Synthetic Vaccines (Synthvaccine): Principles, Design Strategies, and Clinical ApplicationsRead more
Vaccine
Comparative Analysis of Vaccine Vector Technologies
Comparative Analysis of Vaccine Vector Technologies Vaccine vectors, as a cornerstone of modern vaccinology, are categorized into viral vectors, bacterial vectors, nucleic acid vectors (DNA/mRNA), and synthetic biology vectors. Below is a comprehensive comparison of their advantages, limitations, an … Comparative Analysis of Vaccine Vector TechnologiesRead more
Vector Vaccines: Types and Representative Products
Vector Vaccines: Types and Representative Products Vector vaccines utilize genetic engineering to deliver antigens into host cells, activating the immune system. They are widely applied in infectious disease prevention, cancer therapy, and animal health. Below is a comprehensive analysis of major ve … Vector Vaccines: Types and Representative ProductsRead more
Vector Vaccines: Notable Examples and Applications in Human and Animal Health
Vector Vaccines: Notable Examples and Applications in Human and Animal Health I. Viral Vector Vaccines 1. Human Medicine a. Adenoviral Vectors COVID-19 Vaccines: ChAdOx1 (AstraZeneca): A chimpanzee adenovirus vector delivers the SARS-CoV-2 spike protein gene, achieving ~70% efficacy with a single do … Vector Vaccines: Notable Examples and Applications in Human and Animal HealthRead more
LNP Vax: Breakthroughs and Clinical Pathways for Lung Cancer Prevention
LNP Vax: Breakthroughs and Clinical Pathways for Lung Cancer Prevention As the leading cause of global cancer mortality, lung cancer prevention has long been constrained by limitations in early screening. The LNP Vax, a lipid nanoparticle (LNP)-based preventive vaccine, is revolutionizing protection … LNP Vax: Breakthroughs and Clinical Pathways for Lung Cancer PreventionRead more
Contraindications of COVID-19 Antiviral Therapies: A Comprehensive Analysis
Contraindications of COVID-19 Antiviral Therapies: A Comprehensive Analysis (As of May 2025) I. Key Contraindications of Major Antivirals 1. Paxlovid (Nirmatrelvir/Ritonavir) Absolute Contraindications: Hypersensitivity to nirmatrelvir or ritonavir (e.g., Stevens-Johnson syndrome, toxic epidermal ne … Contraindications of COVID-19 Antiviral Therapies: A Comprehensive AnalysisRead more
Comprehensive Analysis of SARS-CoV-2 Variants and Emerging Treatments
Comprehensive Analysis of SARS-CoV-2 Variants and Emerging Treatments (As of May 2025) I. Key Variants and Epidemiological Features 1. Dominant Circulating Variants XBB.1.5 (“Kraken”): Transmissibility: WHO designates it as the most transmissible Omicron subvariant, with a 3–5x higher R0 … Comprehensive Analysis of SARS-CoV-2 Variants and Emerging TreatmentsRead more
Integrating Viral Vector Technologies with Artificial Intelligence: Key Case Studies
Integrating Viral Vector Technologies with Artificial Intelligence: Key Case Studies (Comprehensive Review as of May 2025) The convergence of viral vector technologies and artificial intelligence (AI) is revolutionizing gene therapy, vaccine development, and precision medicine. By leveraging AI-driv … Integrating Viral Vector Technologies with Artificial Intelligence: Key Case StudiesRead more