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Vector Vaccines: Notable Examples and Applications in Human and Animal Health

Vector Vaccines: Notable Examples and Applications in Human and Animal Health I. Viral Vector Vaccines 1. Human Medicine a. Adenoviral Vectors COVID-19 Vaccines: ChAdOx1 (AstraZeneca): A chimpanzee adenovirus vector delivers the SARS-CoV-2 spike protein gene, achieving ~70% efficacy with a single do … Vector Vaccines: Notable Examples and Applications in Human and Animal HealthRead more

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LNP Vax: Breakthroughs and Clinical Pathways for Lung Cancer Prevention

LNP Vax: Breakthroughs and Clinical Pathways for Lung Cancer Prevention As the leading cause of global cancer mortality, lung cancer prevention has long been constrained by limitations in early screening. The LNP Vax, a lipid nanoparticle (LNP)-based preventive vaccine, is revolutionizing protection … LNP Vax: Breakthroughs and Clinical Pathways for Lung Cancer PreventionRead more

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Contraindications of COVID-19 Antiviral Therapies: A Comprehensive Analysis

Contraindications of COVID-19 Antiviral Therapies: A Comprehensive Analysis (As of May 2025) I. Key Contraindications of Major Antivirals 1. Paxlovid (Nirmatrelvir/Ritonavir) Absolute Contraindications: Hypersensitivity to nirmatrelvir or ritonavir (e.g., Stevens-Johnson syndrome, toxic epidermal ne … Contraindications of COVID-19 Antiviral Therapies: A Comprehensive AnalysisRead more

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Comprehensive Analysis of SARS-CoV-2 Variants and Emerging Treatments

Comprehensive Analysis of SARS-CoV-2 Variants and Emerging Treatments (As of May 2025) I. Key Variants and Epidemiological Features 1. Dominant Circulating Variants XBB.1.5 (“Kraken”): Transmissibility: WHO designates it as the most transmissible Omicron subvariant, with a 3–5x higher R0 … Comprehensive Analysis of SARS-CoV-2 Variants and Emerging TreatmentsRead more

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Integrating Viral Vector Technologies with Artificial Intelligence: Key Case Studies

Integrating Viral Vector Technologies with Artificial Intelligence: Key Case Studies (Comprehensive Review as of May 2025) The convergence of viral vector technologies and artificial intelligence (AI) is revolutionizing gene therapy, vaccine development, and precision medicine. By leveraging AI-driv … Integrating Viral Vector Technologies with Artificial Intelligence: Key Case StudiesRead more

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Splice Genes in Protein Diversity and Tissue-Specific Regulation: Advances and Applications

Splice Genes in Protein Diversity and Tissue-Specific Regulation: Advances and Applications I. Biological Basis of Alternative Splicing and Protein Diversity 1. Prevalence and Molecular Mechanisms Alternative splicing, a central post-transcriptional regulatory mechanism, generates multiple mRNA isof … Splice Genes in Protein Diversity and Tissue-Specific Regulation: Advances and ApplicationsRead more