Neuroendocrine Neoplasms (NENs): A Comprehensive Overview I. Definition and Classification Neuroendocrine neoplasms (NENs) are heterogeneous tumors arising from peptidergic neurons and neuroendocrine cells, characterized by neuroendocrine differentiation and hormone or bioactive peptide secretion. A … Neuroendocrine Neoplasms (NENs): A Comprehensive OverviewRead more
SYN
Syn (Synapsin): A synaptic vesicle-associated protein that regulates neurotransmitter release.
Protein Engineering in Synthetic Biology: Recent Advances and Future Prospects
Protein Engineering in Synthetic Biology: Recent Advances and Future Prospects The convergence of synthetic biology and protein engineering is redefining biotechnology. Recent breakthroughs in protein design, optimization, and application—powered by gene editing, AI, and cross-scale engineering stra … Protein Engineering in Synthetic Biology: Recent Advances and Future ProspectsRead more
Applications and Innovations of Biosensors in Drug Screening
Applications and Innovations of Biosensors in Drug Screening Biosensors have revolutionized drug screening with their high sensitivity, real-time monitoring, and target-specific recognition. Below, we categorize key examples by technological principles and application scenarios, highlighting breakth … Applications and Innovations of Biosensors in Drug ScreeningRead more
The Pivotal Role of High-Precision Sensors in Synthetic Biology
The Pivotal Role of High-Precision Sensors in Synthetic Biology High-precision sensors are central to achieving dynamic control, real-time monitoring, and precision design in synthetic biology, with applications spanning fundamental research to industrial deployment. Below, we dissect their multidim … The Pivotal Role of High-Precision Sensors in Synthetic BiologyRead more
Core Challenges in Synthetic Biology Kinetics: A Deep Dive
Core Challenges in Synthetic Biology Kinetics: A Deep Dive I. Foundational Challenges in Model Construction Parameterization Challenges & Data Noise Kinetic models (e.g., ODEs, FBA) for synthetic biosystems rely heavily on experimental parameters such as enzymatic reaction rates (kcatkcat) and … Core Challenges in Synthetic Biology Kinetics: A Deep DiveRead more
Synthetic Biology Kinetics（synbiok）: Theoretical Foundations for Rational Design of Biosystems
Synthetic Biology Kinetics: Theoretical Foundations for Rational Design of Biosystems Synthetic biology kinetics bridges quantitative modeling and biological system engineering, providing a mathematical framework to predict and control the dynamic behavior of engineered biological systems. This disc … Synthetic Biology Kinetics（synbiok）: Theoretical Foundations for Rational Design of BiosystemsRead more
Synthetic Biology: Key Directions in Gene Manipulation
Synthetic Biology: Key Directions in Gene Manipulation I. Foundational Gene-Editing Technologies DNA Synthesis & Assembly Chemical Synthesis: Solid-phase phosphodiester bond-based synthesis produces single-stranded DNA up to 200–300 bp, enabling full gene synthesis (e.g., artificial yeast chromo … Synthetic Biology: Key Directions in Gene ManipulationRead more
Synaptophysin: Biological Expression and Cutting-Edge Advances
Synaptophysin: Biological Expression and Cutting-Edge Advances I. Core Concepts of Synaptophysin Biosynthesis Definition Synaptophysin (SYP), a 38 kDa transmembrane glycoprotein belonging to the tetraspanin family, is predominantly localized on presynaptic vesicle membranes in neurons (constituting … Synaptophysin: Biological Expression and Cutting-Edge AdvancesRead more