GenoFus: Precision Detection of Gene Fusions in Lung Cancer and Targeted Therapy Decision-Making GenoFus is an integrated gene fusion detection system combining next-generation sequencing (NGS), artificial intelligence (AI), and multi-omics analysis, designed for precision lung cancer treatment. Bel … GenoFus: Precision Detection of Gene Fusions in Lung Cancer and Targeted Therapy Decision-MakingRead more
Rna
Ribonucleic Acid (RNA) is a crucial biomolecule involved in genetic information transfer and protein synthesis. Unlike DNA, RNA is typically single-stranded and participates in diverse cellular processes.
RNA Scan: Spatial Transcriptomics and Spatiotemporal RNA Dynamics Analysis
RNA-Scan: Spatial Transcriptomics and Spatiotemporal RNA Dynamics Analysis RNA localization and dynamics are central to cellular function regulation. Recent advances in spatial transcriptomics (ST) enable researchers to analyze RNA distribution and dynamics at subcellular to tissue scales. RNA-Scan, … RNA Scan: Spatial Transcriptomics and Spatiotemporal RNA Dynamics AnalysisRead more
Why Are RNA Primers Used Instead of DNA in DNA Replication?
Why Are RNA Primers Used Instead of DNA in DNA Replication? DNA replication is a fundamental molecular process, and the use of RNA primers over DNA primers involves intricate biochemical mechanisms and evolutionary logic. Below is a multi-dimensional analysis of this phenomenon: I. Functional Limita … Why Are RNA Primers Used Instead of DNA in DNA Replication?Read more
Core Types of RNA Therapy and Breakthroughs in Rare Disease Treatment
Core Types of RNA Therapy and Breakthroughs in Rare Disease Treatment RNA therapies precisely regulate disease by targeting various stages of gene expression. Below is an analysis of their core types, recent advancements in rare diseases, and future directions. I. Core Types of RNA Therapy Antisense … Core Types of RNA Therapy and Breakthroughs in Rare Disease TreatmentRead more
RNA Modifications: From Disease Mechanisms to Precision Medicine and Tumor Microenvironment
RNA Modifications: From Disease Mechanisms to Precision Medicine and Tumor Microenvironment RNA modifications—such as m6A, m5C, ac4C, and Ψ—dynamically regulate gene expression programs, serving as a nexus connecting disease pathogenesis, tumor microenvironment (TME) remodeling, and precision medici … RNA Modifications: From Disease Mechanisms to Precision Medicine and Tumor MicroenvironmentRead more
Technical Features of RNA Scan in Viral Detection, Disease Diagnosis, and Biological Research
Technical Features of RNA Scan in Viral Detection, Disease Diagnosis, and Biological Research RNA Scan, a technology system centered on RNA molecule detection (including RNAscope, opn-SATORI, and RIC-seq), demonstrates unique advantages in virology, clinical medicine, and fundamental biology through … Technical Features of RNA Scan in Viral Detection, Disease Diagnosis, and Biological ResearchRead more
Innovations and Applications in RNA Tool Development
Innovations and Applications in RNA Tool Development RNA tool development is undergoing unprecedented technological advancements, spanning breakthroughs from basic sequence analysis to complex structural prediction, and from single-molecule manipulation to system-level regulation. This article explo … Innovations and Applications in RNA Tool DevelopmentRead more
Modified RNA in Therapeutics and Vaccines: Mechanisms, Applications, and Future Challenges
Modified RNA in Therapeutics and Vaccines: Mechanisms, Applications, and Future Challenges Modified RNA technology enhances RNA stability, translation efficiency, and immune regulation through chemical or sequence engineering, making it a cornerstone of modern drug and vaccine development. Below, we … Modified RNA in Therapeutics and Vaccines: Mechanisms, Applications, and Future ChallengesRead more