mRNA Speed: Accelerated Development and Production Technologies mRNA Speed refers to the end-to-end acceleration of mRNA vaccines and therapeutics from sequence design to large-scale production. By integrating modular platforms, synthetic biology innovations, and industrialized manufacturing systems … mRNA Speed: Accelerated Development and Production TechnologiesRead more
mRNA
Messenger RNA (mRNA) is a single-stranded RNA molecule that carries genetic instructions from DNA to ribosomes for protein synthesis.
Applications and Key Advances of mRNA Velocity
Applications and Key Advances of mRNA Velocity mRNA Velocity is a groundbreaking analytical technique based on single-cell RNA sequencing (scRNA-seq) that quantifies the dynamic ratio of unspliced to spliced mRNA to predict future cellular states and developmental trajectories. By adding a temporal … Applications and Key Advances of mRNA VelocityRead more
Gene Therapy and Protein Replacement Therapies: Recent Advances in Restoring Abnormal Gene Function
Gene Therapy and Protein Replacement Therapies: Recent Advances in Restoring Abnormal Gene Function (as of May 2025) I. Gene Therapy: From Single-Gene Repair to Cancer Immunotherapy Revolution Gene therapy corrects or compensates for defective genes through strategies such as gene editing, gene augm … Gene Therapy and Protein Replacement Therapies: Recent Advances in Restoring Abnormal Gene FunctionRead more
SynBio V: Engineering Viral Vectors for mRNA Vaccine Design and Production
SynBio V: Engineering Viral Vectors for mRNA Vaccine Design and Production Integrating Viral Delivery Systems with Synthetic Biology Tools 1. Technological Foundations: Synthetic Biology Reengineering of Viral Vectors Viral vectors, as core mRNA delivery tools, require synthetic biology modification … SynBio V: Engineering Viral Vectors for mRNA Vaccine Design and ProductionRead more
Synthetic mRNA Applications in Vaccine Development and Gene Therapy
Synthetic mRNA Applications in Vaccine Development and Gene Therapy I. Vaccine Development Advancements Infectious Disease Prevention: • Demonstrated rapid response capability through COVID-19 vaccine success • Expanding applications include: RSV, influenza, and Zika virus candidates in clinical tri … Synthetic mRNA Applications in Vaccine Development and Gene TherapyRead more
Velo mRNA: Decoding Dynamic mRNA Patterns via RNA Velocity Theory
Velo mRNA: Decoding Dynamic mRNA Patterns via RNA Velocity Theory RNA velocity is a computational method that quantifies the relative abundance of unspliced and spliced mRNAs to reveal dynamic gene expression changes. By modeling transcriptional kinetics, it predicts future cellular states, enabling … Velo mRNA: Decoding Dynamic mRNA Patterns via RNA Velocity TheoryRead more
mRNA Velocity in Cancer: Advances in Transcription Rate Mutations and Therapeutic Prospects
mRNA Velocity in Cancer: Advances in Transcription Rate Mutations and Therapeutic Prospects mRNA velocity—defined as the elongation rate of RNA polymerase during transcription and the dynamic lifecycle of mRNA from synthesis to degradation—has emerged as a critical factor in cancer biology. Aberrant … mRNA Velocity in Cancer: Advances in Transcription Rate Mutations and Therapeutic ProspectsRead more
Comparative Analysis of mRNA Velocity and Traditional Single-Cell Transcriptomic Approaches
Comparative Analysis of mRNA Velocity and Traditional Single-Cell Transcriptomic Approaches RNA Velocity is a kinetic model that predicts future transcriptional states of single cells by analyzing the ratio of unspliced to spliced mRNA. Unlike traditional single-cell methods (e.g., pseudotime trajec … Comparative Analysis of mRNA Velocity and Traditional Single-Cell Transcriptomic ApproachesRead more