AI-Driven Drug Discovery (BioAI Pharma): Development of Life Science Large Models (Comprehensive Analysis Based on 2025 Technological Advances and Industry Practices) 1. Core Architecture and Data Integration in Life Science Models BioAI Pharma relies on multimodal life science models that integrate … AI-Driven Drug Discovery (BioAI Pharma): Development of Life Science Large ModelsRead more
CRISPR
CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) is a revolutionary gene-editing technology derived from a natural bacterial immune system.
Key points:
Uses a guide RNA to direct the Cas9 protein to cut specific DNA sequences.
Allows precise insertion, deletion, or modification of genes.
Applications: curing genetic diseases, improving crops, biomedical research.
Nobel Prize in Chemistry (2020) awarded to Doudna & Charpentier for its discovery.
It’s faster, cheaper, and more accurate than older gene-editing methods.
Key Challenges in Alzheimer’s Disease Gene Therapy (2025 Assessment)
Key Challenges in Alzheimer’s Disease Gene Therapy Despite advances in target selection, delivery systems, and clinical strategies, Alzheimer’s disease (AD) gene therapy faces critical challenges: 1. Blood-Brain Barrier (BBB) and Delivery Efficiency Penetration Limits: The BBB blocks >95% of macr … Key Challenges in Alzheimer’s Disease Gene Therapy (2025 Assessment)Read more
Latest Advances in Alzheimer’s Disease Gene Therapy Clinical Trials
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CRISPR-FAST: Future Applications (Post-Maturation in 2025)
CRISPR-FAST: Future Applications (Post-Maturation in 2025) CRISPR-FAST (Far-red light-Activated Split-Cas9) is an ultrafast gene-editing technology leveraging far-red light activation, offering spatiotemporal precision, deep tissue penetration (>5 mm), and low off-target risks. Below are its pote … CRISPR-FAST: Future Applications (Post-Maturation in 2025)Read more
CRISPR-FAST: Ultrafast Light-Activated Gene Editing Technology and Its Core Applications
CRISPR-FAST: Ultrafast Light-Activated Gene Editing Technology and Its Core Applications CRISPR-FAST (Far-red light-Activated Split-Cas9) is a groundbreaking gene-editing technology that uses far-red light to activate split Cas9 enzymes (N-Cas9 and C-Cas9), enabling spatiotemporal control of DNA mod … CRISPR-FAST: Ultrafast Light-Activated Gene Editing Technology and Its Core ApplicationsRead more
PlasmidHub: Advancing CRISPR Gene Editing and Vaccine Development
PlasmidHub: Advancing CRISPR Gene Editing and Vaccine Development (2025 Update) As a critical infrastructure in biotechnology, PlasmidHub accelerates innovation in gene editing and vaccine development through standardized, optimized CRISPR plasmid tools. Below are its key contributions in these fiel … PlasmidHub: Advancing CRISPR Gene Editing and Vaccine DevelopmentRead more
Emerging Applications of Metagenomics and High-Throughput Sequencing
Emerging Applications of Metagenomics and High-Throughput Sequencing The integration of metagenomics and high-throughput sequencing (NGS) is revolutionizing life sciences, medicine, and environmental research by enabling culture-free analysis of microbial communities. This synergy deciphers the comp … Emerging Applications of Metagenomics and High-Throughput SequencingRead more
Latest Advances and Future Prospects in Gene Editing, Synthetic Biology, and AI Integration
Latest Advances and Future Prospects in Gene Editing, Synthetic Biology, and AI Integration (2025 Update) I. Gene Editing: From Precision Targeting to Full Gene Integration 1. Breakthrough in evoCAST Gene Editing Tool Achievement: The evoCAST tool, co-developed by David Liu’s team (MIT/Harvard Broad … Latest Advances and Future Prospects in Gene Editing, Synthetic Biology, and AI IntegrationRead more