Exon Editing: Advances and Prospects in Genetic Disease and Cancer Therapy Exon editing, an emerging technology that precisely modulates RNA splicing or directly modifies DNA exon sequences to correct pathogenic variants or regulate gene expression, combines innovations in gene editing (e.g., CRISPR … Exon Editing: Advances and Prospects in Genetic Disease and Cancer TherapyRead more
CRISPR
CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) is a revolutionary gene-editing technology derived from a natural bacterial immune system.
Key points:
Uses a guide RNA to direct the Cas9 protein to cut specific DNA sequences.
Allows precise insertion, deletion, or modification of genes.
Applications: curing genetic diseases, improving crops, biomedical research.
Nobel Prize in Chemistry (2020) awarded to Doudna & Charpentier for its discovery.
It’s faster, cheaper, and more accurate than older gene-editing methods.
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