AI and Big Data-Driven Longevity Medicine: 2025 Advances and Frontiers I. Multimodal Data Integration and Aging Mechanism Analysis The core breakthrough of AI and big data lies in transforming heterogeneous data into actionable biological insights, mapping aging across molecular to systemic dimensio … AI and Big Data-Driven Longevity Medicine: 2025 Advances and FrontiersRead more
CRISPR
CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) is a revolutionary gene-editing technology derived from a natural bacterial immune system.
Key points:
Uses a guide RNA to direct the Cas9 protein to cut specific DNA sequences.
Allows precise insertion, deletion, or modification of genes.
Applications: curing genetic diseases, improving crops, biomedical research.
Nobel Prize in Chemistry (2020) awarded to Doudna & Charpentier for its discovery.
It’s faster, cheaper, and more accurate than older gene-editing methods.
Global Advances in Longevity Technology and Age Extension
Global Advances in Longevity Technology and Age Extension (2025 Comprehensive Report) I. Breakthroughs in Gene Technology 1. Precision Regulation of Longevity Genes KAT7 Silencing: A team led by Guanghui Liu at the Chinese Academy of Sciences (CAS) used CRISPR/Cas9 to knockout the pro-aging gene KAT … Global Advances in Longevity Technology and Age ExtensionRead more
Gene Technology: Breakthroughs in Longevity Gene Discovery
Gene Technology: Breakthroughs in Longevity Gene Discovery Recent advances in gene technology have accelerated the exploration of longevity genes, revealing molecular mechanisms of aging and identifying potential targets for anti-aging therapies. Through interdisciplinary approaches—including evolut … Gene Technology: Breakthroughs in Longevity Gene DiscoveryRead more
Gene Therapy for Alzheimer’s Disease: Breakthroughs and Challenges
Gene Therapy for Alzheimer’s Disease: Breakthroughs and Challenges (As of May 2025) I. Core Therapeutic Strategies Alzheimer’s disease (AD) gene therapy focuses on modulating genetic risk factors, repairing neuronal damage, and inhibiting pathological protein accumulation (e.g., β-amyloid [Aβ] and t … Gene Therapy for Alzheimer’s Disease: Breakthroughs and ChallengesRead more
Genetic Diseases in Active Gene Editing Clinical Trials and Progress
Genetic Diseases in Active Gene Editing Clinical Trials and Progress (As of May 2025, based on global clinical trial data) I. Hematologic Disorders 1. Sickle Cell Disease (SCD) & β-Thalassemia Candidate Therapies: exa-cel (CTX001): Co-developed by CRISPR Therapeutics and Vertex, this therapy act … Genetic Diseases in Active Gene Editing Clinical Trials and ProgressRead more
Genetic Diseases Treatable with Gene Editing and Key Case Studies
Genetic Diseases Treatable with Gene Editing and Key Case Studies (As of May 2025) Gene editing technologies, particularly CRISPR-Cas9, have enabled precise interventions for monogenic disorders while making breakthroughs in polygenic diseases, mitochondrial disorders, and rare conditions. Below is … Genetic Diseases Treatable with Gene Editing and Key Case StudiesRead more
Can Gene Editing Eradicate Cancer? A Multidimensional Analysis
Can Gene Editing Eradicate Cancer? A Multidimensional Analysis Gene editing technologies—particularly CRISPR-Cas9 and its derivatives—show revolutionary potential in cancer treatment. However, whether they can truly “eradicate cancer” requires a comprehensive analysis across three dimens … Can Gene Editing Eradicate Cancer? A Multidimensional AnalysisRead more
Latest Applications of Gene Editing in Genetic Disease Treatment
Latest Applications of Gene Editing in Genetic Disease Treatment (As of May 2025) Gene editing technologies are revolutionizing the treatment of genetic disorders. Below is a systematic review of recent advancements across four dimensions: technical breakthroughs, clinical applications, multi-system … Latest Applications of Gene Editing in Genetic Disease TreatmentRead more