Genome Engineering and Synthetic Genomics: Technological Paradigms, Differences, and Collaborative Evolution I. Core Definitions and Scope Comparison Genome Engineering Definition: A set of technologies for precise editing, deletion, or insertion of DNA sequences to modify an organism’s genome local … Genome Engineering and Synthetic Genomics: Technological Paradigms, Differences, and Collaborative EvolutionRead more
BIO
BIO Introduction
Biological Foundations and Mathematical Models of RNA Velocity
Biological Foundations and Mathematical Models of RNA Velocity RNA Velocity is a dynamic analysis method based on single-cell transcriptomics (scRNA-seq). By quantifying the abundance differences between unspliced and spliced mRNAs, it infers the direction and rate of gene expression changes in cell … Biological Foundations and Mathematical Models of RNA VelocityRead more
BioAIPharma Applications and Case Studies: AI-Driven Transformation in Biopharmaceuticals
BioAIPharma Applications and Case Studies: AI-Driven Transformation in Biopharmaceuticals Artificial Intelligence (AI) is revolutionizing biopharmaceutical research and development (BioAIPharma), permeating every stage from target discovery to clinical trials, manufacturing, and precision medicine. … BioAIPharma Applications and Case Studies: AI-Driven Transformation in BiopharmaceuticalsRead more
Core Definition and Multidisciplinary Applications of Biocyclic Systems
Core Definition and Multidisciplinary Applications of Biocyclic Systems Biocyclic systems, as an interdisciplinary concept, focus on emulating the material and energy flow patterns of natural ecosystems to achieve sustainability through closed-loop cycles, resource regeneration, and process optimiza … Core Definition and Multidisciplinary Applications of Biocyclic SystemsRead more
Challenges and Future Directions of CRISPR Technology
Challenges and Future Directions of CRISPR Technology Despite CRISPR’s revolutionary potential in precision medicine and gene therapy, its large-scale clinical application faces multiple challenges. Below, we outline key technical bottlenecks and future directions, integrating current research … Challenges and Future Directions of CRISPR TechnologyRead more
Can Synthetic Biology (SynBio) Create New Species?
Can Synthetic Biology (SynBio) Create New Species? Synthetic Biology (SynBio), a revolutionary interdisciplinary field, aims to engineer biological systems to design or construct entirely new species not found in nature. Rapid advancements have shifted this field from theory to practice, revealing b … Can Synthetic Biology (SynBio) Create New Species?Read more
Synthetic Biology (SynBio) and Artificial Life Systems: From Theory to Practice
Synthetic Biology (SynBio) and Artificial Life Systems: From Theory to Practice Synthetic Biology (SynBio) is revolutionizing life sciences by engineering biological systems to create or redesign life forms that transcend natural evolutionary limits. As a critical branch of SynBio, artificial life s … Synthetic Biology (SynBio) and Artificial Life Systems: From Theory to PracticeRead more
Synthetic Biology (SynBio) and Cell/Gene Therapy: Technological Revolution and Clinical Applications
Synthetic Biology (SynBio) and Cell/Gene Therapy: Technological Revolution and Clinical Applications Synthetic Biology (SynBio) is transforming cell and gene therapy (CGT) through the engineering of biological systems. By integrating biology and engineering, SynBio enables modular, programmable rede … Synthetic Biology (SynBio) and Cell/Gene Therapy: Technological Revolution and Clinical ApplicationsRead more